A large number of allergens have been discovered but we know little about their potential to induce inflammation (allergenic activity) and symptoms. Nowadays, the clinical importance of allergens is determined by the frequency and intensity of their IgE antibody binding (allergenicity).
This is a rather limited parameter considering the development of experimental allergology in the last 20 years and the criteria that support personalized medicine. Now it is known that some allergens, in addition to their IgE antibody binding properties, can induce inflammation through non IgE mediated pathways, which can increase their allergenic activity.
There are several ways to evaluate the allergenic activity, among them the provocation tests, the demonstration of non-IgE mediated pathways of inflammation, case control studies of IgE-binding frequencies, and animal models of respiratory allergy.
REAGENT BOTTLE,500 ML, PP |
1500P-500 |
CORNING |
10/pk |
EUR 62 |
Description: Reusable Plastics; Resusable Bottles |
DBCO-PEG-Biotin,500 |
HE048041-500-100mg |
Biochempeg |
100mg |
EUR 765 |
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
PLGA(50:50)?8K?-PEG-Mal,500 |
HE086022-500-500mg |
Biochempeg |
500mg |
EUR 765 |
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
Alkyne CPG modifier 500, 500 mg |
32860 |
Lumiprobe |
500 mg |
EUR 193 |
miRZip-500 anti-miR-500 microRNA construct |
MZIP500-PA-1 |
SBI |
Bacterial Streak |
EUR 684 |
|
FAM CPG 500, 6-isomer, 500 mg |
35760 |
Lumiprobe |
500 mg |
EUR 249 |
TFA-Amino modifier CPG 500, 500 mg |
31860 |
Lumiprobe |
500 mg |
EUR 193 |
Measuring Spoon 500 |
MSP05 |
Next Advance |
25pack |
EUR 123 |
Description: 500uL (0.5mL) measuring spoon. Ideal for aliquoting beads into tubes. |
ZeptoGel (500 mL) |
0801195 |
Zeptometrix |
500 mL |
EUR 327.68 |
|
Description: Please contact Gentaur in order to receive the datasheet of the product. |
Cellufine A-500 |
675980335 |
JNC America |
10 lt |
Ask for price |
Cellufine Q-500 |
675982335 |
JNC America |
10 lt |
Ask for price |
Cellufine C-500 |
675983335 |
JNC America |
10 lt |
Ask for price |
mPEG-SH,500 |
33-MF001003-500 |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-COOH?500 |
33-MF001017-500 |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
mPEG-MAL,500 |
33-MF001022-500 |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
500 ML SPINNER FLASK, 100 MM CENTRE NECK, 2 X 45 MM SIDEARMS |
4500-500 |
CORNING |
1/pk |
EUR 529 |
Description: Bioprocess Vessels; Spinner Flask 70 |
TUBE,MICENT,1.7ML,NAT,SC,NS,BK,500/500 |
3620 |
CORNING |
500/pk |
EUR 56 |
Description: Microcentrifuge Tubes; Snap Cap Tubes |
cleaning solution 500 ml |
B530 |
Consort |
ea |
EUR 30 |
500 G HEPES, POWDER |
61-034-RO |
CORNING |
500 g/pk |
EUR 146 |
Description: Media Catalog; Cell Culture Reagents |
PLASTIC CLAMP, 500 ML |
480151 |
CORNING |
1/pk |
EUR 70 |
Description: Lab Equipment; Constant Temperature Equipment |
MC Cellufine C-500 |
19-800-51 |
JNC America |
5 x 1 ml |
EUR 217 |
MC Cellufine C-500 |
19-800-55 |
JNC America |
5 x 5 ml |
EUR 345 |
MC Cellufine A-500 |
19-805-51 |
JNC America |
5 x 1 ml |
EUR 217 |
MC Cellufine A-500 |
19-805-55 |
JNC America |
5 x 5 ml |
EUR 345 |
MC Cellufine Q-500 |
19-907-51 |
JNC America |
5 x 1 ml |
EUR 217 |
MC Cellufine Q-500 |
19-907-55 |
JNC America |
5 x 5 ml |
EUR 345 |
MC Cellufine S-500 |
21-200-51 |
JNC America |
5 x 1 ml |
EUR 239 |
MC Cellufine S-500 |
21-200-55 |
JNC America |
5 x 5 ml |
EUR 420 |
HO-PEG-COOH,500 |
33-HE002017-500 |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SH-PEG-COOH,500 |
33-HE003017-500 |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
HS-PEG-NHS,500 |
33-HE003023-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
NH2-PEG-COOH,500 |
33-HE005017-500 |
Biochempeg |
|
|
Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
N3-PEG-OH,500 |
33-HE006002-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
N3-PEG-BIOTIN,500 |
33-HE006041-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
Biotin-PEG-COOH,500 |
33-HE041017-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SH-PEG-SH,500 |
33-HO003003-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
AlKyne-PEG-AlKyne,500 |
33-HO007007-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
COOH-PEG-COOH,500 |
33-HO017017-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
SC-PEG-SC,500 |
33-HO023023-500 |
Biochempeg |
|
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Description: A high purity chemical with various applications in medical research, drug-release, nanotechnology and new materials research, cell culture. In the study of ligand, polypeptide synthesis support, a graft polymer compounds, new materials, and polyethylene glycol-modified functional coatings and other aspects of the active compound. |
BMZEROâ„¢, 500 ml |
401 |
AthenaES |
500 ml |
EUR 105 |
EPM2â„¢, 500 ml |
402 |
AthenaES |
500 ml |
EUR 107 |
HPC1â„¢, 500 ml |
403 |
AthenaES |
500 ml |
EUR 110 |
Refolding Buffers - 500 ml |
612 |
AthenaES |
500 ml |
EUR 247 |
Augmediumâ„¢, Powder 500 |
124 |
AthenaES |
500 ml |
EUR 566 |
mmu-miR-500 Primers |
MPM00559 |
ABM |
150 ul / 10 uM |
EUR 121 |
rno-miR-500 Primers |
MP-r00247 |
ABM |
150 ul / 10 uM |
EUR 176 |
THPTA ligand, 500 mg |
H4050 |
Lumiprobe |
500 mg |
EUR 216 |
electrolyte 500 ml 4m licl |
B525 |
Consort |
ea |
EUR 121 |
Compact Balance, 500 grams, 115V |
BCM1302 |
Bio Basic |
1 pcs, 1 UNIT |
EUR 456.19 |
|
Precision Balance, 500 grams, 115V |
BCM1308 |
Bio Basic |
1 pcs, 1 UNIT |
EUR 1479.17 |
|
Measuring Spoon 500 RNase Free |
MSP05-RNA |
Next Advance |
10pack |
EUR 136 |
Description: 500uL (0.5mL) measuring spoon. Ideal for aliquoting beads into tubes. RNase free. |
500 ML HYBRIGRO SFâ„¢ |
40-215-CVR |
CORNING |
500 mL/pk |
EUR 200 |
Description: Specialty Media; Serum Free and Specialty Media |
500 G L-GLUTAMINE, POWDER |
61-030-RO |
CORNING |
500 g/pk |
EUR 199 |
Description: Media Catalog; Cell Culture Reagents |
500 G POLYSUCROSE 400, POWDER |
61-196-RO |
CORNING |
500 g/pk |
EUR 507 |
Description: Specialty Media; Insect Media Products |
500 G YEAST EXTRACT, POWDER |
61-231-RO |
CORNING |
500 g/pk |
EUR 178 |
Description: Media Catalog; Cell Culture Reagents |
BioRad CFX96, Megabase 500/1000 |
A28241L |
GeneOn |
5x25 pcs |
EUR 303 |
500 ML SODIUM CHLORIDE, 5M |
46-032-CV |
CORNING |
500 mL/pk |
EUR 90 |
Description: Media Catalog; Classical Media |
500 ML MCDB 131, 1X |
15-100-CV |
CORNING |
500 mL/pk |
EUR 132 |
Description: Media Catalog; Classical Media |
SharpProtein MarkerII unit: 500 µl |
FYP005-500UL |
Yeastern Biotech |
1 vial |
Ask for price |
Polyclonal CDC6 Antibody (aa400-500) |
APR02453G |
Leading Biology |
0.05ml |
EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human CDC6 (aa400-500). This antibody is tested and proven to work in the following applications: |
Polyclonal ZBTB2 Antibody (aa450-500) |
APR02982G |
Leading Biology |
0.05mg |
EUR 484 |
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human ZBTB2 (aa450-500). This antibody is tested and proven to work in the following applications: |
Cal-500™, potassium salt |
20410 |
AAT Bioquest |
10x50 ug |
EUR 219 |
|
P4-8Fâ„¢, 500 ml |
404 |
AthenaES |
500 ml |
EUR 107 |
LB*Boosterâ„¢, Powder 500 |
126 |
AthenaES |
500 ml |
EUR 190 |
APF LB Lennox, 500 g |
132 |
AthenaES |
500 g |
EUR 107 |
mmu-miR-500-3p Primers |
MPM01366 |
ABM |
150 ul / 10 uM |
EUR 121 |
mmu-miR-500-5p Primers |
MPM01367 |
ABM |
150 ul / 10 uM |
EUR 121 |
In this review we have explored the current status of basic and clinical research on allergenic activity of indoor allergens and confirm that, for most of them, this important property has not been investigated.
However, during recent years important advances have been made in the field, and we conclude that for at least the following, allergenic activity has been demonstrated: Der p 1, Der p 2, Der p 5 and Blo t 5 from HDMs; Per a 10 from P. americana; Asp f 1, Asp f 2, Asp f 3, Asp f 4 and Asp f 6 from A. fumigatus; Mala s 8 and Mala s 13 from M. sympodialis; Alt a 1 from A. alternata; Pen c 13 from P. chrysogenum; Fel d 1 from cats; Can f 1, Can f 2, Can f 3, Can f 4 and Can f 5 from dogs; Mus m 1 from mice and Bos d 2 from cows. Defining the allergenic activity of other indoor IgE antibody binding molecules is necessary for a precision-medicine-oriented management of allergic diseases.