Applications: IHC, WB.
Reactive species: Human
AFX/FOXO4 information: Molecular
Weight: 53684 MW; Subcellular
Localization: Cytoplasm. Nucleus.
When phosphorylated, translocated out of the nucleus to cytoplasm. Nuclear translocation is triggered by dephosphorylation. Nuclear localization is increased by monoubiquitination. When deubiquitinated, translocated from nucleus into cytoplasm; Tissue Specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is abundant in the liver, kidney, and pancreas.